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Looking for the latest developments in vision research? Review some of the newest academic publications here, updated regularly:

2021

Age-Related Macular Degeneration (AMD)

  • Okada M, Wong TY, Mitchell P, et al. Defining Nonadherence and Nonpersistence to Anti-Vascular Endothelial Growth Factor Therapies in Neovascular Age-Related Macular Degeneration. JAMA Ophthalmol. Published online June 3, 2021. doi:10.1001/jamaophthalmol.2021.1660
  • Wagner BD, Patnaik JL, Palestine AG, et al. Association of Systemic Inflammatory Factors with Progression to Advanced Age-related Macular Degeneration. Ophthalmic Epidemiol. Published online April 8, 2021:1-10. doi:10.1080/09286586.2021.1910314
  • Thomas CN, Sim DA, Lee WH, et al. Emerging therapies and their delivery for treating age-related macular degeneration. Br J Pharmacol. Published online March 26, 2021. doi:10.1111/bph.15459
  • Kumar Dubey S, Pradhan R, Hejmady S, et al. Emerging innovations in nano-enabled therapy against age-related macular degeneration: A paradigm shift. International Journal of Pharmaceutics. Published online March 19, 2021:120499. doi:10.1016/j.ijpharm.2021.120499
  • Wittich W, Pichora-Fuller MK, Johnson A, et al. Effect of Reading Rehabilitation for Age-Related Macular Degeneration on Cognitive Functioning: Protocol for a Nonrandomized Pre-Post Intervention Study. JMIR Res Protoc. 2021;10(3):e19931. doi:10.2196/19931
  • Bucan K, Lukic M, Bosnar D, et al. Analysis of association of risk factors for age-related macular degeneration. Eur J Ophthalmol. Published online March 4, 2021:1120672121998900. doi:10.1177/1120672121998900
  • Zhuang J, Madden DJ, Cunha P, et al. Cerebral white matter connectivity, cognition, and age-related macular degeneration. Neuroimage Clin. 2021;30:102594. doi:10.1016/j.nicl.2021.102594
  • Kloosterboer A, Yannuzzi N, Topilow N, Patel N, Kuriyan A, Sridhar J. Assessing the Quality, Content, and Readability of Freely Available Online Information for Patients Regarding Age-Related Macular Degeneration. Semin Ophthalmol. Published online March 1, 2021:1-6. doi:10.1080/08820538.2021.1893761
  • Achiron A, Elbaz U, Hecht I, et al. The Effect of Blue-Light Filtering Intraocular Lenses on the Development and Progression of Neovascular Age-Related Macular Degeneration. Ophthalmology. 2021;128(3):410-416. doi:10.1016/j.ophtha.2020.07.039
  • Sim SS, Yip MY, Wang Z, et al. Digital Technology for AMD Management in the Post-COVID-19 New Normal. Asia Pac J Ophthalmol (Phila). 2021;10(1):39-48. doi:10.1097/APO.0000000000000363
  • Hyttinen JMT, Blasiak J, Felszeghy S, Kaarniranta K. Micro-RNAs in the regulation of autophagy and their possible use in age-related macular degeneration therapy. Ageing Res Rev. Published online January 28, 2021:101260. doi:10.1016/j.arr.2021.101260
  • Martinez B, Peplow PV. MicroRNAs as diagnostic and prognostic biomarkers of age-related macular degeneration: advances and limitations. Neural Regen Res. 2021;16(3):440-447. doi:4103/1673-5374.293131
  • Lee W-JA, Yang Y-HK, Cheng C-L. Risk of age-related macular degeneration in aspirin users and non-aspirin users: A population-based cohort study in Taiwan. Pharmacoepidemiol Drug Saf. 2021;30(2):178-188. doi:1002/pds.5145
  • Grant A, Colman I, Freeman EE. Impact of the Improper Adjustment for Age in Research on Age-Related Macular Degeneration: An Example Using Data from the Canadian Longitudinal Study on Aging. Ophthalmic Epidemiol. 2021;28(1):86-89. doi:1080/09286586.2020.1853179
  • Chua SYL, Warwick A, Peto T, et al. Association of ambient air pollution with age-related macular degeneration and retinal thickness in UK Biobank. Br J Ophthalmol. Published online January 25, 2021. doi:1136/bjophthalmol-2020-316218
  • Dillon L, Gandhi S, Tang D, et al. Perspectives of people with late age-related macular degeneration on mental health and mental wellbeing programmes: a qualitative study. Ophthalmic Physiol Opt. Published online January 11, 2021. doi:1111/opo.12779
  • Di Spirito F, La Rocca M, De Bernardo M, Rosa N, Sbordone C, Sbordone L. Possible Association of Periodontal Disease and Macular Degeneration: A Case-Control Study. Dentistry Journal. 2021;9(1):1. doi:3390/dj9010001

Cataracts

  • Owen JP, Blazes M, Lacy M, et al. Refractive Outcomes After Immediate Sequential vs Delayed Sequential Bilateral Cataract Surgery. JAMA Ophthalmol. Published online July 1, 2021. doi:10.1001/jamaophthalmol.2021.2032
  • Ridderskär L, Montan P, Kugelberg M, et al. Outcome of cataract surgery in eyes with diabetic retinopathy: a Swedish national cataract register report. Acta Ophthalmol. Published online May 27, 2021. doi:10.1111/aos.14914
  • Wang W, Han X, Zhang J, et al. Predicting the 10-year risk of cataract surgery using machine learning techniques on questionnaire data: findings from the 45 and Up Study. British Journal of Ophthalmology. Published online May 26, 2021. doi:10.1136/bjophthalmol-2020-318609
  • Starr MR, Mahr MA, Smith WM, Iezzi R, Barkmeier AJ, Bakri SJ. Outcomes of patients with active diabetic macular edema at the time of cataract surgery managed with intravitreal anti-VEGF injections: Outcomes of cataract surgery in active DME patients. Am J Ophthalmol. Published online April 11, 2021. doi:10.1016/j.ajo.2021.04.002
  • Kanakamedala A, Go JA, Wendt S, Ugoh P, Khan M, Al-Mohtaseb Z. Systemic and Ocular Comorbidities of Black, Hispanic, and White Women with Cataracts. J Womens Health (Larchmt). Published online April 7, 2021. doi:10.1089/jwh.2020.8793
  • Leffler CT, Schwartz SG, Peterson E, Couser NL, Salman A-R. The First Cataract Surgeons in the British Isles. Am J Ophthalmol. Published online March 17, 2021. doi:10.1016/j.ajo.2021.03.009
  • Campbell RJ, El-Defrawy SR, Gill SS, et al. Surgical Outcomes among Focused versus Diversified Cataract Surgeons. Ophthalmology. Published online February 23, 2021. doi:10.1016/j.ophtha.2021.01.016
  • Chua SY, Luben RN, Hayat S, et al. Alcohol Consumption and Incident Cataract Surgery in Two Large UK Cohorts. Ophthalmology. Published online February 8, 2021. doi:10.1016/j.ophtha.2021.02.007
  • Rossi T, Romano MR, Iannetta D, et al. Cataract surgery practice patterns worldwide: a survey. BMJ Open Ophthalmol. 2021;6(1):e000464. doi:10.1136/bmjophth-2020-000464
  • Chen CL, McLeod SD, Lietman TM, et al. Preoperative Medical Testing and Falls in Medicare Beneficiaries Awaiting Cataract Surgery. Ophthalmology. 2021;128(2):208-215. doi:10.1016/j.ophtha.2020.09.013
  • Bolletta E, Coassin M, Iannetta D, et al. Cataract Surgery with Intraocular Lens Implantation in Juvenile Idiopathic Arthritis-Associated Uveitis: Outcomes in the Era of Biological Therapy. J Clin Med. 2021;10(11). doi:10.3390/jcm10112437

Diabetic Retinopathy (DR)

  • Chen H, Pan X, Yang J, et al. Application of 5G Technology to Conduct Real-Time Teleretinal Laser Photocoagulation for the Treatment of Diabetic Retinopathy. JAMA Ophthalmol. Published online July 8, 2021. doi:10.1001/jamaophthalmol.2021.2312
  • Azad N, Agrawal L, Bahn G, et al. Eye Outcomes in Veteran Affairs Diabetes Trial (VADT) After 17 Years. Diabetes Care. Published online June 29, 2021:dc202882. doi:10.2337/dc20-2882
  • Shan Y, Xu Y, Ye L, et al. Socioeconomic disparity in global vision loss burden due to diabetic retinopathy: an analysis on time trends from 1990 to 2017. Endocrine. Published online June 8, 2021. doi:10.1007/s12020-021-02692-3
  • Cao J, Felfeli T, Merritt R, Brent MH. Sociodemographics Associated With Risk of Diabetic Retinopathy Detected by Tele-Ophthalmology: 5-Year Results of the Toronto Tele-Retinal Screening Program. Can J Diabetes. Published online May 8, 2021. doi:10.1016/j.jcjd.2021.05.001
  • Bastos de Carvalho A, Lee Ware S, Belcher T, et al. Evaluation of multi-level barriers and facilitators in a large diabetic retinopathy screening program in federally qualified health centers: a qualitative study. Implement Sci Commun. 2021;2(1):54. doi:10.1186/s43058-021-00157-2
  • Kim D, Choi SW, Cho J, et al. Discovery of Novel Small-Molecule Antiangiogenesis Agents to Treat Diabetic Retinopathy. J Med Chem. Published online April 26, 2021. doi:10.1021/acs.jmedchem.0c01965
  • Cheung N, Chee ML, Klein R, et al. Incidence and progression of diabetic retinopathy in a multi-ethnic US cohort: the Multi-Ethnic Study of Atherosclerosis. Br J Ophthalmol. Published online March 19, 2021. doi:10.1136/bjophthalmol-2021-318992
  • Stanimirovic A, Francis T, Cooper Reed A, et al. Impact of Intersecting Systems of Oppression on Diabetic Retinopathy Screening Among Those Who Identify as Women of Low Socioeconomic Status: Protocol for a Convergent Mixed Methods Study. JMIR Res Protoc. 2021;10(3):e23492. doi:10.2196/23492
  • Zou Y, You W, Wang J, et al. Depression and retinopathy in patients with type 2 diabetes mellitus: A meta-analysis. Psychosom Med. Published online February 27, 2021. doi:10.1097/PSY.0000000000000924
  • Dong Y, Liu Y, Yu J, Qi S, Liu H. Mapping research trends in diabetic retinopathy from 2010 to 2019: A bibliometric analysis. Medicine (Baltimore). 2021;100(3):e23981. doi:10.1097/MD.0000000000023981
  • Kr S, Mk A, X Z, et al. Cost-effectiveness of Interventions to Manage Diabetes: Has the Evidence Changed Since 2008? Diabetes care. doi:10.2337/dci20-0017
  • Gregorio A, Vice S, Witt A, et al. The association between taking a course or class in self-managing diabetes with diabetic ocular complications including diabetic retinopathy: A cross-sectional study. Prim Care Diabetes. 2021;15(1):121-125. doi:1016/j.pcd.2020.06.007
  • Wolf RM, Liu TYA, Thomas C, et al. The SEE Study: Safety, Efficacy, and Equity of Implementing Autonomous Artificial Intelligence for Diagnosing Diabetic Retinopathy in Youth. Diabetes Care. Published online January 21, 2021. doi:2337/dc20-1671
  • Wykoff CC, Khurana RN, Nguyen QD, et al. Risk of Blindness Among Patients With Diabetes and Newly Diagnosed Diabetic Retinopathy. Diabetes Care. Published online January 20, 2021. doi:2337/dc20-0413
  • Arenas-Cavalli JT, Abarca I, Rojas-Contreras M, Bernuy F, Donoso R. Clinical validation of an artificial intelligence-based diabetic retinopathy screening tool for a national health system. Eye (Lond). Published online January 11, 2021. doi:1038/s41433-020-01366-0
  • Broadbent DM, Wang A, Cheyne CP, et al. Safety and cost-effectiveness of individualised screening for diabetic retinopathy: the ISDR open-label, equivalence RCT. Diabetologia. 2021;64(1):56-69. doi:1007/s00125-020-05313-2
  • Silverberg EL, Sterling TW, Williams TH, Castro G, Rodriguez de la Vega P, Barengo NC. The Association between Social Determinants of Health and Self-Reported Diabetic Retinopathy: An Exploratory Analysis. International Journal of Environmental Research and Public Health. 2021;18(2):792. doi:3390/ijerph18020792

Glaucoma

  • Vinod K, Gedde SJ, Ramulu PY. The American Glaucoma Society 100: Articles with Significant Impact on Clinical Glaucoma Care. Ophthalmol Glaucoma. Published online June 28, 2021:S2589-4196(21)00157-5. doi:10.1016/j.ogla.2021.06.002
  • Naufal F, Gajwani P, Medina R, Dutson M, Mariotti SP, West SK. Knowledge of patient emotional health status: impact on clinical care in glaucoma and retinal services. BMJ Open Ophthalmol. 2021;6(1):e000640. doi:10.1136/bmjophth-2020-000640
  • Nuzzi R, Marolo P, Nuzzi A. What Is New in Glaucoma: From Treatment to Biological Perspectives. J Ophthalmol. 2021;2021:5013529. doi:10.1155/2021/5013529
  • Kang JM, Chatterjee A, Rosdahl JA, et al. Health literacy and success with glaucoma drop administration. Ophthalmol Glaucoma. Published online May 27, 2021. doi:10.1016/j.ogla.2021.05.004
  • Kim J, Aschard H, Kang JH, et al. Intraocular Pressure, Glaucoma, and Dietary Caffeine Consumption: A Gene–Diet Interaction Study from the UK Biobank. Ophthalmology. 2021;128(6):866-876. doi:10.1016/j.ophtha.2020.12.009
  • Miller DJ, Niziol LM, Elam AR, et al. Demographic, Clinical, and Psychosocial Predictors of Change in Medication Adherence in the Support, Educate, Empower (SEE) Program. Ophthalmol Glaucoma. Published online June 4, 2021. doi:10.1016/j.ogla.2021.06.001
  • Mincione F, Nocentini A, Supuran CT. Advances in the discovery of novel agents for the treatment of glaucoma. Expert Opin Drug Discov. Published online April 29, 2021. doi:10.1080/17460441.2021.1922384
  • Kass MA, Heuer DK, Higginbotham EJ, et al. Assessment of Cumulative Incidence and Severity of Primary Open-Angle Glaucoma Among Participants in the Ocular Hypertension Treatment Study After 20 Years of Follow-up. JAMA Ophthalmol. Published online April 15, 2021. doi:10.1001/jamaophthalmol.2021.0341
  • Garric C, Rouland J-F, Lenoble Q. Glaucoma and Computer Use: Do Contrast and Color Enhancements Improve Visual Comfort in Patients? Ophthalmology Glaucoma. 2021;0(0). doi:10.1016/j.ogla.2021.01.006
  • Kuzhuppilly NIR, Pai H V, Daruka R, Jain V, Menon S. A Novel Approach to Measuring Binocular Visual Fields in Glaucoma. J Glaucoma. Published online April 2, 2021. doi:10.1097/IJG.0000000000001845
  • Home Monitoring for Glaucoma: Current Applications and Future Directions: Seminars in Ophthalmology: Vol 0, No 0. Accessed March 11, 2021. doi:10.1080/08820538.2021.1896759
  • Qureshi R, Azuara-Blanco A, Michelessi M, et al. What do we really know about the effectiveness of glaucoma interventions: An overview of systematic reviews. Ophthalmol Glaucoma. Published online February 8, 2021. doi:10.1016/j.ogla.2021.01.007
  • Pujari R, Chan G, Tapply I, Bourne RR. The impacts of COVID-19 on glaucoma patient outcomes as assessed by POEM. Eye. Published online February 9, 2021:1-3. doi:10.1038/s41433-021-01425-0
  • Waksmunski AR, Song YE, Kinzy TG, et al. The GGLEAM Study: Understanding Glaucoma in the Ohio Amish. Int J Environ Res Public Health. 2021;18(4). doi:10.3390/ijerph18041551
  • Garric C, Rouland J-F, Lenoble Q. Glaucoma and computer use: do contrast and color enhancements improve visual comfort in patients? Ophthalmol Glaucoma. Published online February 5, 2021. doi:10.1016/j.ogla.2021.01.006
  • Ikeda MC, Bando AH, Hamada KU, et al. Is Reading Performance Impaired in Glaucoma Patients with Preserved Central Vision? J Glaucoma. Published online February 3, 2021. doi:10.1097/IJG.0000000000001806
  • Boland MV, Corcoran KJ, Lee AY. Changes in performance of glaucoma surgeries 1994-2017 based on claims and payment data for US Medicare beneficiaries. Ophthalmol Glaucoma. Published online January 30, 2021. doi:10.1016/j.ogla.2021.01.004
  • Sanchez FG, Mansberger SL, Kung Y, et al. Novel Eye Drop Delivery Aid Improves Outcomes and Satisfaction. Ophthalmol Glaucoma. Published online January 11, 2021. doi:10.1016/j.ogla.2021.01.001
  • Iezhitsa I, Agarwal R. New solutions for old challenges in glaucoma treatment: is taurine an option to consider? Neural Regen Res. 2021;16(5):967-971. doi:4103/1673-5374.297059
  • Baxter SL, Saseendrakumar BR, Paul P, et al. Predictive Analytics for Glaucoma using Data from the All of Us Research Program. Am J Ophthalmol. Published online January 23, 2021. doi:1016/j.ajo.2021.01.008
  • Rhodes LA, Register S, Asif I, et al. Alabama Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (AL-SIGHT): Study Design and Methodology. J Glaucoma. Published online January 22, 2021. doi:1097/IJG.0000000000001794
  • Shin DY, Jung KI, Park HYL, Park CK. The effect of anxiety and depression on progression of glaucoma. Sci Rep. 2021;11(1):1769. doi:1038/s41598-021-81512-0
  • Hark LA, Kresch YS, De Moraes CG, et al. Manhattan Vision Screening and Follow-up Study in Vulnerable Populations (NYC-SIGHT): Design and Methodology. J Glaucoma. Published online January 22, 2021. doi:1097/IJG.0000000000001795
  • Quinn MP, Johnson D, Whitehead M, Gill SS, Campbell RJ. Distribution and Predictors of Initial Glaucoma Care among Ophthalmologists and Optometrists: A Population-based Study. J Glaucoma. Published online January 13, 2021. doi:1097/IJG.0000000000001792
  • Murata H, Asaoka R, Fujino Y, et al. Comparing the usefulness of a new algorithm to measure visual field using the variational Bayes linear regression in glaucoma patients, in comparison to the Swedish interactive thresholding algorithm. Br J Ophthalmol. Published online January 13, 2021. doi:1136/bjophthalmol-2020-318304
  • Stein JD, Khawaja AP, Weizer JS. Glaucoma in Adults-Screening, Diagnosis, and Management: A Review. JAMA. 2021;325(2):164-174. doi:1001/jama.2020.21899
  • Jorkasky J, Davis M, Lee PP. Potential Impact of COVID-19 Disruptions on the Next Generation of Vision Scientists. JAMA Ophthalmol. Published online July 1, 2021. doi:10.1001/jamaophthalmol.2021.1959
  • Chen EM, Andoh JE, Nwanyanwu K. Socioeconomic and Demographic Disparities in the Utilization of Telemedicine for Ophthalmic Care during the COVID-19 Pandemic. Ophthalmology. 2021;0(0). doi:10.1016/j.ophtha.2021.07.003
  • Yang JM, Moon SY, Lee JY, Agalliu D, Yon DK, Lee SW. COVID-19 morbidity and severity in patients with age-related macular degeneration: a Korean nationwide cohort study. Am J Ophthalmol. Published online June 5, 2021:11881. doi:10.1016/j.ajo.2021.05.024
  • Jevnikar K, Jaki Mekjavic P, Vidovic Valentincic N, Petrovski G, Globocnik Petrovic M. An Update on COVID-19 Related Ophthalmic Manifestations. Ocul Immunol Inflamm. Published online April 7, 2021:1-6. doi:10.1080/09273948.2021.1896008
  • Ung L, Jonas JB, Lietman TM, Chodosh J. COVID-19 and the Unfinished Agenda of VISION 2020. Am J Ophthalmol. 2021;224:30-35. doi:10.1016/j.ajo.2020.11.016
  • Crossland MD, Dekker TM, Hancox J, Lisi M, Wemyss TA, Thomas PBM. Evaluation of a Home-Printable Vision Screening Test for Telemedicine. JAMA Ophthalmology. 2021;139(3):271-277. doi:10.1001/jamaophthalmol.2020.5972
  • Tham Y-C, Husain R, Teo KYC, et al. New digital models of care in ophthalmology, during and beyond the COVID-19 pandemic. Br J Ophthalmol. Published online March 22, 2021. doi:10.1136/bjophthalmol-2020-317683
  • Lindeke-Myers A, Zhao PYC, Meyer BI, et al. Patient Perceptions of SARS-CoV-2 Exposure Risk and Association With Continuity of Ophthalmic Care. JAMA Ophthalmol. Published online March 11, 2021. doi:10.1001/jamaophthalmol.2021.0114
  • Morse AR. The Importance of Patients’ Perspectives in Providing Ophthalmic Care—Lessons From the COVID-19 Pandemic. JAMA Ophthalmol. Published online March 11, 2021. doi:10.1001/jamaophthalmol.2021.0121
  • Azzolini C, Donati S, Premi E, et al. SARS-CoV-2 on Ocular Surfaces in a Cohort of Patients With COVID-19 From the Lombardy Region, Italy. JAMA Ophthalmol. Published online March 4, 2021. doi:10.1001/jamaophthalmol.2020.5464
  • Chau CYC, Chow LLW, Sridhar S, Shih KC. Ophthalmological Considerations for COVID-19 Vaccination in Patients with Inflammatory Eye Diseases and Autoimmune Disorders. Ophthalmol Ther. Published online March 6, 2021. doi:10.1007/s40123-021-00338-1
  • Breazzano MP, Nair AA, Arevalo JF, et al. Frequency of Urgent or Emergent Vitreoretinal Surgical Procedures in the United States During the COVID-19 Pandemic. JAMA Ophthalmol. Published online March 4, 2021. doi:10.1001/jamaophthalmol.2021.0036
  • COVID-19 and Utilization of Teleophthalmology: Trends and Diagnoses (CUT Group) – Ophthalmology. Accessed March 3, 2021. https://www.aaojournal.org/article/S0161-6420(21)00118-4/fulltext
  • Pandey N, Kumar S, Kesar SD, et al. An Ophthalmological update for air-travellers during COVID-19. Travel Med Infect Dis. 2021;39:101955. doi:10.1016/j.tmaid.2020.101955
  • Brady CJ, D’Amico S, Withers N, Kim BY. Using Public Datasets to Identify Priority Areas for Ocular Telehealth. Telemed J E Health. Published online February 18, 2021. doi:10.1089/tmj.2020.0433
  • Jin Y-P, Trope GE, El-Defrawy S, Liu EY, Buys YM. Ophthalmology-focused publications and findings on COVID-19: A systematic review. Eur J Ophthalmol. Published online February 8, 2021:1120672121992949. doi:10.1177/1120672121992949
  • Salica JP, Potilinski C, Querci M, et al. A Year of Living Dangerously: Challenges and Recommendations for Safely Performing Ophthalmic Surgery During the COVID-19 Pandemic, from Start to Finish. Clin Ophthalmol. 2021;15:261-278. doi:10.2147/OPTH.S283327
  • Lambert SR. VISION 2020: what remains to be done after the COVID-19 pandemic? The Lancet Child & Adolescent Health. 2021;0(0). doi:10.1016/S2352-4642(20)30391-6
  • Patel SY, Mehrotra A, Huskamp HA, Uscher-Pines L, Ganguli I, Barnett ML. Variation In Telemedicine Use And Outpatient Care During The COVID-19 Pandemic In The United States. Health Aff (Millwood). 2021;40(2):349-358. doi:10.1377/hlthaff.2020.01786
  • Modjtahedi BS, Zyl T van, Fong DS. Improving Compliance with Vaccinations: A Public Health Opportunity for Ophthalmologists. Ophthalmology. 2020;127(3):293-295. doi:10.1016/j.ophtha.2020.01.022
  • Bhattacharya S, Reddy Maddikunta PK, Pham Q-V, et al. Deep learning and medical image processing for coronavirus (COVID-19) pandemic: A survey. Sustain Cities Soc. 2021;65:102589. doi:1016/j.scs.2020.102589
  • Balestrino A, Robba C, Ceraudo M, et al. Turning tables: a war-like approach to neurosurgical emergencies in the Covid-19. J Neurosurg Sci. Published online January 22, 2021. doi:23736/S0390-5616.21.05226-7
  • Casagrande M, Fitzek A, Spitzer MS, et al. Presence of SARS-CoV-2 RNA in the Cornea of Viremic Patients With COVID-19. JAMA Ophthalmol. Published online January 21, 2021. doi:1001/jamaophthalmol.2020.6339
  • Yan Y, Zeng B, Zhang Z, et al. Detection of SARS-CoV-2 in Simultaneously Collected Tear and Throat Swab Samples from the Patients with 2019- new SARS-CoV-2 Infection Disease: A Single Center Cross-sectional Study. Ophthalmic Epidemiol. Published online January 24, 2021:1-7. doi:1080/09286586.2021.1875011
  • Martin GC, Le Roux G, Guindolet D, et al. Pediatric Eye Injuries by Hydroalcoholic Gel in the Context of the Coronavirus Disease 2019 Pandemic. JAMA Ophthalmol. Published online January 21, 2021. doi:1001/jamaophthalmol.2020.6346
  • Ortiz-Egea JM, Ruiz-Medrano J, Ruiz-Moreno JM. Retinal imaging study diagnoses in COVID-19: a case report. Journal of Medical Case Reports. 2021;15(1):15. doi:1186/s13256-020-02620-5
  • Blumberg S, Borlase A, Prada JM, et al. Implications of the COVID-19 pandemic in eliminating trachoma as a public health problem. Trans R Soc Trop Med Hyg. Published online January 15, 2021. doi:1093/trstmh/traa170
  • Wang J, Li Y, Musch DC, et al. Progression of Myopia in School-Aged Children After COVID-19 Home Confinement. JAMA Ophthalmol. Published online January 14, 2021. doi:1001/jamaophthalmol.2020.6239
  • Sun L, Hymowitz M, Pomeranz HD. Eye Protection for Patients With COVID-19 Undergoing Prolonged Prone-Position Ventilation. JAMA Ophthalmol. 2021;139(1):109-112. doi:1001/jamaophthalmol.2020.4988

Artificial Intelligence

  • Tan T-E, Chan HW, Singh M, et al. Artificial intelligence for diagnosis of inherited retinal disease: an exciting opportunity and one step forward. Br J Ophthalmol. Published online May 24, 2021. doi:10.1136/bjophthalmol-2021-319365
  • Mehta P, Petersen CA, Wen JC, et al. Automated detection of glaucoma with interpretable machine learning using clinical data and multi-modal retinal images. Am J Ophthalmol. Published online May 1, 2021. doi:10.1016/j.ajo.2021.04.021
  • Tan T-E, Anees A, Chen C, et al. Retinal photograph-based deep learning algorithms for myopia and a blockchain platform to facilitate artificial intelligence medical research: a retrospective multicohort study. Lancet Digit Health. 2021;3(5):e317-e329. doi:10.1016/S2589-7500(21)00055-8
  • Bora A, Balasubramanian S, Babenko B, et al. Predicting the risk of developing diabetic retinopathy using deep learning. Lancet Digit Health. 2021;3(1):e10-e19. doi:10.1016/S2589-7500(20)30250-8
  • Yamauchi T, Tabuchi H, Takase K, Masumoto H. Use of a Machine Learning Method in Predicting Refraction after Cataract Surgery. J Clin Med. 2021;10(5). doi:10.3390/jcm10051103
  • Jacoba CMP, Celi LA, Silva PS. Biomarkers for Progression in Diabetic Retinopathy: Expanding Personalized Medicine through Integration of AI with Electronic Health Records. Semin Ophthalmol. Published online March 18, 2021:1-8. doi:10.1080/08820538.2021.1893351
  • Benet D, Pellicer-Valero OJ. Artificial Intelligence: the unstoppable revolution in ophthalmology. Surv Ophthalmol. Published online March 16, 2021. doi:10.1016/j.survophthal.2021.03.003
  • Campbell JP, Singh P, Redd TK, et al. Applications of Artificial Intelligence for Retinopathy of Prematurity Screening. Pediatrics. Published online February 26, 2021. doi:10.1542/peds.2020-016618
  • Maloca PM, Müller PL, Lee AY, et al. Unraveling the deep learning gearbox in optical coherence tomography image segmentation towards explainable artificial intelligence. Commun Biol. 2021;4(1):170. doi:10.1038/s42003-021-01697-y
  • Shigueoka LS, Mariottoni EB, Thompson AC, Jammal AA, Costa VP, Medeiros FA. Predicting Age From Optical Coherence Tomography Scans With Deep Learning. Transl Vis Sci Technol. 2021;10(1):12. doi:10.1167/tvst.10.1.12
  • Keenan TDL, Clemons TE, Domalpally A, et al. Retinal Specialist versus Artificial Intelligence Detection of Retinal Fluid from OCT: Age-Related Eye Disease Study 2: 10-Year Follow-On Study. Ophthalmology. 2021;128(1):100-109. doi:1016/j.ophtha.2020.06.038
  • Chang J, Lee J, Ha A, et al. Explaining the Rationale of Deep Learning Glaucoma Decisions with Adversarial Examples. Ophthalmology. 2021;128(1):78-88. doi:1016/j.ophtha.2020.06.036
  • Ng WY, Cheung CY, Milea D, Ting DSW. Artificial intelligence and machine learning for Alzheimer’s disease: let’s not forget about the retina. British Journal of Ophthalmology. Published online January 24, 2021. doi:1136/bjophthalmol-2020-318407
  • Chakraborty R, Pramanik A. Deep Learning-Based Automated Detection of Age-Related Macular Degeneration from Retinal Fundus Images. In: Bhattacharjee D, Kole DK, Dey N, Basu S, Plewczynski D, eds. Proceedings of International Conference on Frontiers in Computing and Systems. Advances in Intelligent Systems and Computing. Springer; 2021:433-441. doi:1007/978-981-15-7834-2_41
  • Hsieh Y-T, Chuang L-M, Jiang Y-D, et al. Application of deep learning image assessment software VeriSeeTM for diabetic retinopathy screening. J Formos Med Assoc. 2021;120(1 Pt 1):165-171. doi:1016/j.jfma.2020.03.024
  • Gallardo M, Munk MR, Kurmann T, et al. Machine learning can predict anti-VEGF treatment demand in a Treat-and-Extend regimen for patients with nAMD, DME and RVO associated ME. Oph Retina. 2021;0(0). doi:10.1016/j.oret.2021.05.002
  • Campbell JP, Kim SJ, Brown JM, et al. Evaluation of a Deep Learning–Derived Quantitative Retinopathy of Prematurity Severity Scale. Ophthalmology. 2021;128(7):1070-1076. doi:10.1016/j.ophtha.2020.10.025

Devices

  • Sahel J-A, Boulanger-Scemama E, Pagot C, et al. Partial recovery of visual function in a blind patient after optogenetic therapy. Nature Medicine. Published online May 24, 2021:1-7. doi:10.1038/s41591-021-01351-4
  • Lyu Q, Peng L, Hong X, et al. Smart nano-micro platforms for ophthalmological applications: The state-of-the-art and future perspectives. Biomaterials. 2021;270:120682. doi:10.1016/j.biomaterials.2021.120682
  • Brodie F, Repka M, Burns SA, et al. Development, Validation, and Innovation in Ophthalmic Laser-Based Imaging: Report From a US Food and Drug Administration-Cosponsored Forum. JAMA Ophthalmol. 2021;139(1):113-118. doi:10.1001/jamaophthalmol.2020.4994
  • Khurana RN, Hoang C, Khanani AM, Steklov N, Singerman LJ. A Smart Mobile Application to Monitor Visual Function in Diabetic Retinopathy and Age-related Macular Degeneration: The CLEAR Study: Mobile Device for Measuring Visual Acuity and Function. American Journal of Ophthalmology. 2021;0(0). doi:10.1016/j.ajo.2021.03.033
  • Chow LS, Paley MNJ. Recent advances on optic nerve magnetic resonance imaging and post-processing. Magnetic Resonance Imaging. 2021;79:76-84. doi:10.1016/j.mri.2021.03.014
  • Shin H, Seo H, Chung WG, Joo BJ, Jang J, Park J-U. Recent progress on wearable point-of-care devices for ocular systems. Lab Chip. Published online March 11, 2021. doi:10.1039/d0lc01317j

Geriatrics

  • Vu TA, Fenwick EK, Gan ATL, et al. The Bidirectional Relationship between Vision and Cognition: A Systematic Review and Meta-analysis. Ophthalmology. 2021;128(7):981-992. doi:10.1016/j.ophtha.2020.12.010
  • Kahiel Z, Grant A, Aubin M-J, Buhrmann R, Kergoat M-J, Freeman EE. Vision, Eye Disease, and the Onset of Balance Problems: The Canadian Longitudinal Study on Aging: Vision and Balance Problems. Am J Ophthalmol. Published online June 19, 2021:S0002-9394(21)00330-5. doi:10.1016/j.ajo.2021.06.008
  • Wen L-Y, Wan L, Lai J-N, et al. Increased risk of Alzheimer’s disease among patients with age-related macular degeneration: A nationwide population-based study. PLoS One. 2021;16(5):e0250440. doi:10.1371/journal.pone.0250440
  • Mushumbusi E, Buchan J, Mactaggart I, Macleod D, Foster A. A Systematic Review of the Proportion of Blindness in the Population 50 Years and Older from Total Population-Based Surveys of Blindness and Visual Impairment. Ophthalmic Epidemiol. Published online May 4, 2021:1-7. doi:10.1080/09286586.2021.1918176
  • Ramulu PY, Mihailovic A, Jian-Yu E, et al. Environmental features contributing to falls in persons with vision impairment: The role of home lighting and home hazards. Am J Ophthalmol. Published online May 2, 2021. doi:10.1016/j.ajo.2021.04.022
  • Swain TA, McGwin G, Wood JM, Antin JF, Owsley C. Naturalistic Driving Techniques and Association of Visual Risk Factors With At-Fault Crashes and Near Crashes by Older Drivers With Vision Impairment. JAMA Ophthalmol. Published online April 29, 2021. doi:10.1001/jamaophthalmol.2021.0862
  • Halawa O, Mitchell W, Zebardast N. Fall-related eye injury among older adults in the United States. Am J Ophthalmol. Published online April 10, 2021. doi:10.1016/j.ajo.2021.03.063
  • Hwang PH, Longstreth WT, Thielke SM, et al. Ophthalmic conditions associated with dementia risk: The Cardiovascular Health Study. Alzheimers Dement. Published online March 31, 2021. doi:10.1002/alz.12313
  • Laroche D, Capellan P. The Aging Lens and Glaucoma in persons over 50: Why early cataract surgery/refractive lensectomy and microinvasive trabecular bypass can prevent blindness and cure elevated eye pressure. J Natl Med Assoc. Published online March 26, 2021. doi:10.1016/j.jnma.2021.03.001
  • Shang X, Zhu Z, Wang W, He M. Associations of vision impairment and eye diseases with memory decline over four years in China and the United States. Am J Ophthalmol. Published online March 24, 2021. doi:10.1016/j.ajo.2021.03.021
  • Mullany S, Xiao L, Qassim A, et al. Normal-tension glaucoma is associated with cognitive impairment. British Journal of Ophthalmology. Published online February 26, 2021. doi:10.1136/bjophthalmol-2020-317461
  • Jin W, Yao Q, Liu Z, et al. Do eye diseases increase the risk of arthritis in the elderly population? Aging (Albany NY). 2021;13. doi:10.18632/aging.203122

Pediatrics

  • Enthoven CA, Polling JR, Verzijden T, et al. Smartphone use associated with refractive error in teenagers; the Myopia app Study. Ophthalmology. 2021;0(0). doi:10.1016/j.ophtha.2021.06.016
  • Wysocka-Mincewicz M, Gołębiewska J, Baszyńska-Wilk M, Olechowski A. Gender-Specific Risk Factors for the Development of Retinal Changes in Children with Type 1 Diabetes. J Pers Med. 2021;11(6):588. doi:10.3390/jpm11060588
  • Nordt M, Gomez J, Natu VS, et al. Cortical recycling in high-level visual cortex during childhood development. Nat Hum Behav. Published online June 17, 2021:1-12. doi:10.1038/s41562-021-01141-5
  • Lee H-J, Kim YK, Jeoung JW, Park KH, Kim S-J. Visual outcomes and associated factors of primary congenital glaucoma in children. Graefes Arch Clin Exp Ophthalmol. Published online June 2, 2021. doi:10.1007/s00417-021-05232-x
  • Lee SS-Y, McVeigh J, Straker L, et al. Physical Activity and Cardiovascular Fitness During Childhood and Adolescence: Association With Retinal Nerve Fibre Layer Thickness in Young Adulthood. J Glaucoma. Published online May 11, 2021. doi:10.1097/IJG.0000000000001865
  • Stewart C, Coffey-Sandoval J, Reid MW, Ho TC, Lee TC, Nallasamy S. Reliability of telemedicine for real-time paediatric ophthalmology consultations. British Journal of Ophthalmology. Published online March 15, 2021. doi:10.1136/bjophthalmol-2020-318385
  • Wahl MD, Fishman D, Block SS, et al. A Comprehensive Review of State Vision Screening Mandates for Schoolchildren in the United States. Optom Vis Sci. Published online May 7, 2021. doi:10.1097/OPX.0000000000001686
  • Cavuoto KM, Vanner EA, Osigian CJ. Trends in pediatric ocular trauma presenting to an ophthalmology-specific emergency department during the COVID-19 pandemic. J AAPOS. Published online April 28, 2021. doi:10.1016/j.jaapos.2021.01.004
  • Morale SE, Cheng-Patel CS, Jost RM, Donohoe N, Leske DA, Birch EE. Normative pediatric visual acuity using electronic early treatment for diabetic retinopathy protocol. J AAPOS. Published online April 24, 2021. doi:10.1016/j.jaapos.2021.01.003
  • Mudie LI, Guo X, Slavin RE, et al. Baltimore Reading and Eye Disease Study: vision outcomes of school-based eye care. Can J Ophthalmol. Published online March 18, 2021. doi:10.1016/j.jcjo.2021.02.013
  • Prevalence of Ophthalmologic Diagnoses in Children With Autism Spectrum Disorder Using the Optum Dataset: A Population-Based Study – American Journal of Ophthalmology. Accessed March 5, 2021. https://www.ajo.com/article/S0002-9394(20)30485-2/abstract
  • Haider KM, Wallace DK. Using Adult Drug Efficacy Data to Aid in Interpretation of Underpowered Pediatric Studies. JAMA Ophthalmol. 2021;139(2):217. doi:10.1001/jamaophthalmol.2020.5557
  • Sabharwal S, Nakayoshi A, Lees CR, Perez S, de Alba Campomanes AG. Prevalence and Factors Associated With Eyeglass Wear Compliance Among Preschoolers From Low-Income Families in San Francisco, California. JAMA Ophthalmol. Published online February 18, 2021. doi:10.1001/jamaophthalmol.2020.7053
  • Leske DA, Hatt SR, Wernimont SM, et al. Quality of life and functional vision across pediatric eye conditions assessed using the PedEyeQ. J AAPOS. Published online February 15, 2021. doi:10.1016/j.jaapos.2020.10.010
  • Teoh LJ, Solebo AL, Rahi JS, et al. Visual impairment, severe visual impairment, and blindness in children in Britain (BCVIS2): a national observational study. The Lancet Child & Adolescent Health. 2021;0(0). doi:10.1016/S2352-4642(20)30366-7
  • García-Sánchez A, Villalaín I, Asencio M, García J, García-Rio F. Sleep apnea and eye diseases: evidence of association and potential pathogenic mechanisms. J Clin Sleep Med. Published online July 20, 2021. doi:10.5664/jcsm.9552
  • Trott M, Smith L, Veronese N, et al. Eye disease and mortality, cognition, disease, and modifiable risk factors: an umbrella review of meta-analyses of observational studies. Eye. Published online July 16, 2021:1-10. doi:10.1038/s41433-021-01684-x
  • Wang F, Hadzic S, Roxlau ET, et al. Retinal tissue develops an inflammatory reaction to tobacco smoke and electronic cigarette vapor in mice. J Mol Med (Berl). Published online July 15, 2021. doi:10.1007/s00109-021-02108-9
  • Keel S, Müller A, Block S, et al. Keeping an eye on eye care: monitoring progress towards effective coverage. Lancet Glob Health. Published online July 5, 2021:S2214-109X(21)00212-6. doi:10.1016/S2214-109X(21)00212-6
  • Nousome D, Mckean-Cowdin R, Richter GM, et al. Retinal Nerve Fiber Layer Thickness in Healthy Eyes of Black, Chinese, and Latino Americans: A Population-Based Multiethnic Study. Ophthalmology. 2021;128(7):1005-1015. doi:10.1016/j.ophtha.2020.11.015
  • Hogden K, Mikelberg F, Sodhi M, et al. The association between hormonal contraceptive use and glaucoma in women of reproductive age. Br J Clin Pharmacol. Published online June 22, 2021. doi:10.1111/bcp.14920
  • Chen C, Du K-F, Xie L-Y, et al. Clinical Features of Ocular Pathology in Patients with Acquired Immunodeficiency Syndrome and Syphilis. Adv Ther. Published online May 21, 2021. doi:10.1007/s12325-021-01755-1
  • Marshall-Goebel K, Macias BR, Kramer LA, et al. Association of Structural Changes in the Brain and Retina After Long-Duration Spaceflight. JAMA Ophthalmol. Published online May 20, 2021. doi:10.1001/jamaophthalmol.2021.1400
  • Leiby BE, Hegarty SE, Zhan T, et al. A Randomized Trial to Improve Adherence to Follow-up Eye Examinations Among People With Glaucoma. Prev Chronic Dis. 2021;18:E52. doi:10.5888/pcd18.200567
  • Burr JM, Cooper D, Ramsay CR, Che Hamzah J, Azuara-Blanco A. Interpretation of change scores for the National Eye Institute Visual Function Questionnaire-25: the minimally important difference. Br J Ophthalmol. Published online May 18, 2021. doi:10.1136/bjophthalmol-2021-318901
  • Dada T, Mittal D, Mohanty K, et al. Mindfulness Meditation Reduces Intraocular Pressure, Lowers Stress Biomarkers and Modulates Gene Expression in Glaucoma: A Randomized Controlled Trial. J Glaucoma. 2018;27(12):1061-1067. doi:10.1097/IJG.0000000000001088
  • Das T, Takkar B, Sivaprasad S, et al. Recently updated global diabetic retinopathy screening guidelines: commonalities, differences, and future possibilities. Eye (Lond). Published online May 11, 2021. doi:10.1038/s41433-021-01572-4
  • Ng Yin Ling C, Lim SC, Jonas JB, Sabanayagam C. Obesity and risk of age-related eye diseases: a systematic review of prospective population-based studies. Int J Obes (Lond). Published online May 7, 2021. doi:10.1038/s41366-021-00829-y
  • Khan SM, Liu X, Nath S, et al. A global review of publicly available datasets for ophthalmological imaging: barriers to access, usability, and generalisability. Lancet Digit Health. 2021;3(1):e51-e66. doi:10.1016/S2589-7500(20)30240-5
  • Janetos TM, Thyparampil P. Ocular Cosmetics: Public Safety Problem or Harmless Products? Ophthalmic Plast Reconstr Surg. 2019;35(3):294-295. doi:10.1097/IOP.0000000000001337
  • Moustafa GA, Borkar DS, Eton EA, et al. Healthcare disparities contribute to missed follow-up visits after cataract surgery in the USA: results from the perioperative care for intraocular lens study. BMJ Open. 2021;11(3):e038565. doi:10.1136/bmjopen-2020-038565
  • Study estimates the financial costs, environmental waste generated by single-use plastics. American Academy of Ophthalmology. Published March 12, 2021. Accessed March 22, 2021. https://www.aao.org/editors-choice/study-estimates-financial-costs-environmental-wast
  • Chiam M, Kunselman AR, Chen MC. Characteristics associated with new patient appointment no-shows at an academic ophthalmology department in the United States. Am J Ophthalmol. Published online February 21, 2021. doi:10.1016/j.ajo.2021.02.020
  • Wu AM, Morse AR, Seiple WH, et al. Reduced Mammography Screening for Breast Cancer among Women with Visual Impairment. Ophthalmology. 2021;128(2):317-323. doi:10.1016/j.ophtha.2020.07.029
  • Do blue-blocking lenses reduce eye strain from extended screen time? A double-masked, randomized controlled trial – American Journal of Ophthalmology. Accessed February 23, 2021. https://www.ajo.com/article/S0002-9394(21)00072-6/fulltext
  • Lim JI, Niec M, Sun J, Cao D. Longitudinal Assessment of Retinal Thinning in Adults With and Without Sickle Cell Retinopathy Using Spectral-Domain Optical Coherence Tomography. JAMA Ophthalmol. Published online February 4, 2021. doi:10.1001/jamaophthalmol.2020.6525
  • Assi L, Chamseddine F, Ibrahim P, et al. A Global Assessment of Eye Health and Quality of Life: A Systematic Review of Systematic Reviews. JAMA Ophthalmol. Published online February 12, 2021. doi:10.1001/jamaophthalmol.2021.0146
  • Lovell J, Rabin J, Cerrillo A, et al. Visual distraction from automobile displays: an impediment to visual performance. Eye. Published online February 1, 2021:1-2. doi:10.1038/s41433-021-01409-0
  • Brown GC, Brown MM, Chaudhry I, Stein JD. Opportunities to Reduce Potential Bias in Ophthalmic Cost-Utility Analysis. JAMA Ophthalmol. Published online February 4, 2021. doi:10.1001/jamaophthalmol.2020.6591
  • Luu W, Zangerl B, Kalloniatis M, Palmisano S, Kim J. Vision Impairment Provides New Insight Into Self-Motion Perception. Invest Ophthalmol Vis Sci. 2021;62(2):4. doi:10.1167/iovs.62.2.4
  • Ghaffari R, Aldave AJ, Al-Hashimi S, Miller KM. Complications of Cosmetic Artificial Iris Implantation and Post Explantation Outcomes. American Journal of Ophthalmology. 2021;0(0). doi:1016/j.ajo.2021.01.005
  • Liu Z, Parikh BH, Tan QSW, et al. Surgical Transplantation of Human RPE Stem Cell-Derived RPE Monolayers into Non-Human Primates with Immunosuppression. Stem Cell Reports. 2021;0(0). doi:1016/j.stemcr.2020.12.007
  • Lange R, Kumagai A, Weiss S, et al. Vision-related quality of life in adults with severe peripheral vision loss: a qualitative interview study. J Patient Rep Outcomes. 2021;5(1):7. doi:1186/s41687-020-00281-y
  • Dhoot AS, Koziarz A, Lee Y, Chopra C, Micieli JA. Eye Injuries and Visor Use in the National Football League. Ophthalmology. Published online February 2, 2021. doi:10.1016/j.ophtha.2021.01.027
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